Hepatic steatosis, Alcohol Consumption, and Metabolic Health Over Time

Steatotic liver disease is not always a fixed diagnosis.

New research from the Canadian Longitudinal Study on Aging examined how changes in alcohol use, metabolic health, and hepatic steatosis over time may influence mortality risk.

The findings show that many individuals transitioned between steatotic liver disease subtypes over a three-year period. Mortality risk also increased with higher alcohol consumption, with alcohol-related liver disease (ALD) showing the highest mortality risk compared with MASLD.

Importantly, models that accounted for changes in health and disease status over time revealed risks that traditional static models may underestimate.

Swipe through the carousel to explore the findings, and read the full study in Liver International.